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What is Ehrlichia caused by?

Ehrlichia is caused by a group of tick-borne rickettsial bacteria, primarily Ehrlichia canis, transmitted by ticks such as the brown dog tick.

Understanding Ehrlichia: Causes, Transmission, and Prevention

Ehrlichia is a genus of rickettsial bacteria responsible for causing a serious tick-borne disease in dogs known as ehrlichiosis. This disease is most commonly caused by Ehrlichia canis, which is transmitted primarily through the bite of an infected brown dog tick (Rhipicephalus sanguineus).

How Is Ehrlichia Transmitted?

The disease begins when a dog is bitten by a tick carrying Ehrlichia. Transmission can occur within a few hours, although extended feeding time increases the likelihood of infection. There are several tick species associated with the transmission of different Ehrlichia strains:

  • Rhipicephalus sanguineus – transmits Ehrlichia canis
  • Amblyomma americanum (Lone star tick) – carries Ehrlichia chaffeensis and Ehrlichia ewingii
  • Ixodes scapularis (Black-legged tick) – can spread Ehrlichia muris eauclairensis

It's important to note that dogs cannot directly transmit the disease to each other. However, infection may occur via blood transfusion if an infected dog is unknowingly used as a donor.

Progression and Symptoms of Ehrlichiosis

Once a dog is infected, the disease progresses through three distinct phases:

  1. Acute Phase: Occurs 1–3 weeks post-infection. Symptoms include fever, lethargy, loss of appetite, weight loss, enlarged lymph nodes, joint pain, bleeding, vomiting, diarrhea, and respiratory or neurological issues. This phase may last 2–4 weeks.
  2. Subclinical Phase: The dog shows no overt symptoms but may have lab irregularities like low platelet count. The infection is dormant but can last for months or even years. Some dogs may clear the infection in this stage.
  3. Chronic Phase: Characterized by severe issues including anemia, bleeding disorders, eye infections, increased thirst and urination, swollen limbs, and even bone marrow failure. This phase can be fatal.

Risk Factors

Some breeds are more susceptible to severe forms of the disease, including:

  • German Shepherds
  • Doberman Pinschers
  • Belgian Malinois
  • Siberian Huskies

Diagnostic and Treatment Options

Diagnosing ehrlichiosis typically involves a combination of clinical signs, tick exposure history, and laboratory tests. Methods include:

  • Antibody testing (serology) – Detects exposure but may be negative in early stages
  • PCR testing – Identifies the DNA of Ehrlichia organisms, effective in early infection
  • Blood smears – May rarely reveal Ehrlichia in immune cells
  • Routine bloodwork and urinalysis to assess anemia and organ function

Treatment consists mainly of antibiotics like doxycycline or minocycline for at least four weeks. Alternative treatments include chloramphenicol, imidocarb dipropionate, and rifampicin in specific cases. Dogs with severe illness may require supportive care and blood transfusions.

Preventing Ehrlichiosis

Tick prevention is vital to avoid ehrlichiosis. Strategies include:

  • Year-round use of veterinarian-recommended tick preventatives (topical, oral, collars)
  • Daily tick checks and prompt removal with fine-tipped tweezers
  • Keeping the pet’s living area free of ticks through environmental treatments
  • Avoiding tick-infested areas, especially during peak seasons

No vaccines are currently available against ehrlichiosis, making proactive tick control the best line of defense.

Impact on Humans

Ehrlichiosis is not spread directly from dogs to humans. However, the same ticks that infect dogs can bite humans and transmit related Ehrlichia species, such as E. chaffeensis and E. ewingii. Human symptoms include fever, fatigue, muscle aches, and rash.

When to Seek Emergency Care

Signs in dogs that require immediate veterinary attention:

  • Sudden bleeding (nose, urine)
  • Severe weakness or collapse
  • High fever
  • Seizures or confusion
  • Pale gums
  • Significant swelling

Early detection and treatment are crucial for a good prognosis. Dogs treated in the acute phase often recover fully, whereas chronic cases may lead to lifelong complications or death.

Ongoing Vigilance

In endemic areas or high-risk breeds, regular vet checkups and tick control are vital. Testing can catch asymptomatic infections early, offering the best chance for effective treatment and long-term health.

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