Background
  1. Home
  2. News
  3. FAQ
  4. Why can't you use Advantage 2 on cats?

Why can't you use Advantage 2 on cats?

Advantage II cannot be used on cats or kittens under 8 weeks old or below the minimum weight requirement due to potential health risks.

Why You Shouldn't Use Advantage II on All Cats

When it comes to flea prevention, responsible pet owners know the importance of using safe and effective products. Advantage II for Cats is one of the most recommended topical treatments by veterinarians, but it's not suitable for every feline. Understanding why and when not to use it can help ensure your pet’s safety and well-being.

What Is Advantage II for Cats?

Advantage II is a monthly, topical flea treatment designed specifically for cats and kittens. Its formula includes two active ingredients:
  • Imidacloprid (9.10%) – kills adult fleas
  • Pyriproxyfen (0.46%) – targets flea larvae and eggs
This powerful combination kills fleas on contact, meaning they don’t need to bite to die. The treatment begins working within 12 hours and can kill re-infesting fleas within 2 hours, offering up to 30 days of continuous protection.

Why Can't You Use Advantage II on Certain Cats?

While highly effective, there are some clear safety parameters regarding which animals this product can be used on:
  • Do not use on kittens under 8 weeks old – Their developing systems may not tolerate the active ingredients.
  • Do not use on underweight cats – The product is available in specific weight categories. Using it outside the recommended range can result in overdose or insufficient protection.
  • Not for ingestion – If a cat licks the product, it may cause temporary salivation due to its bitter taste.
  • Monitor special cases – Elderly, debilitated, pregnant, nursing cats, or those on medication should be assessed by a veterinarian before use.

How to Use Advantage II Safely

Safe application is crucial to ensure both the efficacy and safety of the product:
  1. Hold the applicator upright and remove the cap.
  2. Use the reverse side of the cap to break the seal.
  3. Part the cat’s fur at the base of the skull until the skin is visible.
  4. Apply the entire content directly onto the skin.
Applying at the base of the skull minimizes the risk of the cat licking the product. The formula becomes waterproof 24 hours after application and remains fragrance-free.

Things to Consider Before Use

Before administering Advantage II, it's essential to determine if your cat meets the minimum age and weight requirements:
  • Turquoise packaging: for cats 2–5 lbs
  • Orange packaging: for cats 5–9 lbs
  • Purple packaging: for cats over 9 lbs
In the case of heavy infestations, a reapplication might be necessary earlier than four weeks—but only as directed:
  • For kittens: not more often than every 14 days
  • For adult cats: not more often than every 7 days
Once the infestation is under control, you can resume a monthly application schedule.

Potential Risks and Precautions

The product comes with several hazard precautions:
  • Harmful if swallowed
  • Causes moderate eye irritation
  • For external use only
  • Avoid contact with clothing and eyes
Always wash your hands after applying the treatment, and monitor your cat for signs of skin irritation or gastrointestinal upset. If side effects occur, consult your veterinarian immediately.

Environmental and Storage Guidelines

For maximum efficacy and safety, Advantage II should be stored in a cool, dry place out of reach from both children and pets. Empty containers should be disposed of as instructed on the product packaging.

Conclusion

Advantage II is an effective flea control product, but it’s not one-size-fits-all. You should not use it on kittens under 8 weeks old or cats that fall outside the recommended weight categories. Additionally, cats with special health conditions require a vet's assessment before use. By following label directions and considering your cat’s individual health profile, you can safely protect your furry friend against fleas.

Share on:

advantage ii

 cats

 flea treatment

 topical flea prevention

 kitten flea control

 safe flea treatment

 cat health

 veterinary recommended

 monthly flea treatment

 imidacloprid

 pyriproxyfen

 flea larvae

 flea eggs

 indoor cats

 outdoor cats

 weight requirements

 minimum age

 cat skin irritation

 bitter taste

 licking medication

 flea allergy dermatitis

 tapeworm prevention

 flea bite anemia

 topical application

 waterproof flea treatment

Recommended

Fluffy Ragdoll cat with blue eyes sitting near beige water bowl in modern bathroom

Key Signs That Your Cat’s Health Needs Immediate Attention

Read the article

Fluffy silver tabby Maine Coon cat sitting beside a bowl of dry kibble on a wooden deck

Practical feeding guidelines for free-roaming and outdoor cats

Read the article

Maine Coon cat with ear tufts and amber eyes being hand-fed a treat with tweezers indoors

Removing Ticks from Your Cat: Safe Steps and Best Tools

Read the article

Today is the perfect time to get your

Pet Health Report

Upload a photo of your pet to receive instant health and care insights.

report_card