Understanding the Effectiveness of Advantage Multi for Dogs
Advantage Multi for Dogs is a
broad-spectrum, prescription-only topical treatment designed to offer monthly protection to dogs against a wide range of parasites. Developed by Elanco Animal Health, this medication combines two potent active ingredients—
imidacloprid and
moxidectin—to provide comprehensive coverage. This article explores its effectiveness, usage, safety, and more, making it a must-read for any dog owner considering or currently using this treatment.
What Is Advantage Multi for Dogs?
Advantage Multi is a
monthly spot-on treatment applied directly to a dog’s skin. It is approved for use in dogs and puppies that are at least 7 weeks old and weigh at least 3 pounds. It addresses:
- Heartworm prevention (Dirofilaria immitis)
- Flea treatment and control (Ctenocephalides felis)
- Sarcoptic mange (Sarcoptes scabiei var. canis)
- Intestinal parasites such as hookworms, roundworms, and whipworms
How Does it Work?
The effectiveness of Advantage Multi is attributed to its two active components:
- Imidacloprid (10%) – Targets and kills adult fleas by interfering with their nervous system.
- Moxidectin (2.5%) – Prevents heartworm disease and eliminates microfilariae, as well as treats and controls intestinal parasites.
These ingredients are absorbed through the skin and distributed systemically, ensuring full-body protection.
Areas of Effectiveness
1. Heartworm Disease: Advantage Multi is particularly effective in
preventing heartworm disease when administered monthly. It treats infective larvae and circulating microfilariae but does not eliminate adult heartworms, so pre-testing is essential.
2. Fleas: It effectively
kills adult fleas and treats existing flea infestations. Its formulation remains effective even after occasional bathing or exposure to water 90 minutes post-application.
3. Intestinal Parasites: The product treats infections caused by:
- Hookworms: Ancylostoma caninum and Uncinaria stenocephala
- Roundworms: Toxocara canis and Toxascaris leonina
- Whipworms: Trichuris vulpis
4. Sarcoptic Mange: Advantage Multi also addresses
skin infestations caused by mites, significantly improving a dog's skin condition and comfort.
Proper Application & Usage
Application technique is crucial for maximizing effectiveness. Here are step-by-step directions:
- Remove and hold the dose tube upright. Break the seal using the cap.
- Part the dog’s hair between the shoulder blades.
- Apply the contents directly to the skin in one spot (small dogs) or multiple spots (larger dogs).
- Prevent the dog from licking the application site for at least 30 minutes.
Important Usage Notes
- Children should avoid contact with application areas for 2 hours.
- Do not apply to broken or irritated skin.
- Store between 39°F–77°F (4°C–25°C).
- Do not use on cats or other animals.
Safety and Side Effects
Advantage Multi is generally well-tolerated. Most side effects are mild and include:
- Itching at the application site
- Lethargy
- Residue or damp hair at application site
- Medicinal odor
More serious reactions (though rare) can include vomiting, diarrhea, loss of appetite, and neurological symptoms. Accidental ingestion or use in dogs with the MDR1 gene mutation (e.g., Collies) may cause severe toxicity, including coma or death. Always consult a vet if side effects are observed.
Pre-Treatment Requirements
Vet consultation and a
current heartworm test are mandatory before prescribing Advantage Multi. Heartworm-positive dogs should be treated for adult worms before starting.
Dosing Specifics
Dosages vary by the dog’s weight:
- 3–9 lbs: 40 mg imidacloprid, 10 mg moxidectin
- 9.1–20 lbs: 100 mg imidacloprid, 25 mg moxidectin
- 20.1–55 lbs: 250 mg imidacloprid, 62.5 mg moxidectin
- 55.1–88 lbs: 400 mg imidacloprid, 100 mg moxidectin
- 88.1–110 lbs: 500 mg imidacloprid, 125 mg moxidectin
Dogs over 110 lbs require a combination of doses under veterinary supervision.
Effectiveness with Bathing
Advantage Multi remains effective for heartworm prevention even if the dog is shampooed 90 minutes after treatment. However,
frequent bathing—once a week or more—may reduce flea control efficacy.
Missed Dose Protocol
If a dose is missed:
- Administer as soon as remembered.
- Return to monthly schedule.
- Do not double-dose.
- If more than 30 days pass, consult your vet.
Conclusion
Advantage Multi for Dogs is a powerful, multi-purpose solution for protecting dogs against parasitic infestations and infections. When used as directed, it offers
monthly peace of mind for dog owners and promotes
long-term canine health. Speak with your veterinarian today to determine if Advantage Multi is the right choice for your pet.
