Understanding What Advantage Multi Does for Dogs
Advantage Multi for Dogs is a comprehensive, once-monthly topical treatment that addresses multiple parasitic threats to your pet's health. Approved for use in dogs and puppies 7 weeks or older and weighing at least 3 pounds, Advantage Multi combines two active ingredients—
imidacloprid (10%) and
moxidectin (2.5%)—to provide broad-spectrum protection against both external and internal parasites.
Key Benefits of Advantage Multi
- Prevents heartworm disease caused by Dirofilaria immitis
- Kills adult fleas (Ctenocephalides felis) and manages flea infestations
- Treats and controls sarcoptic mange caused by Sarcoptes scabiei var. canis
- Treats and controls intestinal parasites including:
- Hookworms: Ancylostoma caninum, Uncinaria stenocephala
- Roundworms: Toxocara canis, Toxascaris leonina
- Whipworms: Trichuris vulpis
Application Instructions
Follow these steps to apply Advantage Multi effectively:
- Remove one dose tube and hold upright.
- Remove the cap, invert it, and use the other end to break the seal.
- With the dog standing, part the hair between the shoulder blades or along the back.
- Apply contents directly to exposed skin:
- For dogs ≤ 20 lbs: apply to one spot between the shoulder blades.
- For dogs > 20 lbs: apply to 3-4 spots along the back from neck to upper back.
- Prevent licking for 30 minutes; keep children away from the area for 2 hours.
- Resume monthly schedule. If a dose is missed, apply as soon as possible without doubling.
Dosage by Weight
- 3–9 lbs: 40 mg imidacloprid / 10 mg moxidectin
- 9.1–20 lbs: 100 mg imidacloprid / 25 mg moxidectin
- 20.1–55 lbs: 250 mg imidacloprid / 62.5 mg moxidectin
- 55.1–88 lbs: 400 mg imidacloprid / 100 mg moxidectin
- 88.1–110 lbs: 500 mg imidacloprid / 125 mg moxidectin
For dogs over 110 lbs, combine appropriate tube sizes. Always store the product at room temperature (39°F to 77°F) in its original packaging.
Side Effects and Precautions
Most dogs tolerate Advantage Multi well, but some possible side effects may include:
- Itching (pruritus) at application site
- Lethargy or decreased activity
- Temporary dampness or residue at application area
- Vomiting or diarrhea
- Hair loss at application site
More serious side effects such as muscle tremors, salivation, and ataxia have been reported following accidental ingestion. Breeds with the MDR1 gene mutation, like Collies, may be at higher risk of severe reactions. Do not apply if skin is irritated or allow contact with dog’s eyes or mouth.
Special Considerations
- Prescription Required: Advantage Multi is available only through a veterinarian.
- Heartworm Testing: Dogs should be tested annually and before starting treatment.
- Compatibility: Do not use with other heartworm or flea preventatives.
- Shampooing: Bathing 90 minutes post-treatment does not reduce heartworm efficacy. Bathing 4 days after application does not affect flea control, but frequent bathing may reduce effectiveness.
- Use Restrictions: Do not use in cats or administer orally. Not safe for underweight, sick, or less than 7-week-old dogs.
Conclusion
Advantage Multi for Dogs is a powerful and versatile solution for preventing and treating a range of common canine parasites. Its once-monthly application makes it convenient for pet owners, and its broad efficacy helps protect your dog from both internal and external threats. Always follow veterinary advice and read the product label to ensure safe and effective use.
