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What happens if you don't treat Valley fever in dogs?

If untreated, Valley fever in dogs can progress from mild lung disease to widespread dissemination, causing severe pain, organ damage, or even death.

What Happens If You Don’t Treat Valley Fever in Dogs?

Valley fever, or coccidioidomycosis, is a serious fungal infection primarily affecting dogs in the southwestern United States and other arid regions. Caused by the fungus Coccidioides, the disease begins when a dog inhales airborne spores from disturbed soil. In many cases, dogs show no symptoms, but in others, the infection can result in severe illness or even death if not treated.

The Progression of Untreated Valley Fever

When Valley fever is left untreated, the consequences can be extensive and life-threatening. Here’s how the disease typically progresses without medical intervention:

  • Pulmonary Disease: Initial infection usually starts in the lungs. Without treatment, signs like dry cough, fever, and weight loss can worsen.
  • Spread to Other Organs: Spherules in the lungs release numerous endospores, potentially spreading to bones, eyes, skin, and even the nervous system. This leads to disseminated Valley fever, which is far more dangerous.
  • Chronic Pain and Lameness: Infection in the bones and joints can cause severe discomfort, mobility issues, and persistent lameness.
  • Neurological Damage: If the fungus disseminates to the brain, symptoms like seizures and disorientation may occur, often with a poor prognosis.
  • Eye and Skin Problems: Involvement of the eyes may result in blindness, while skin lesions or non-healing wounds often emerge on the body.
  • Organ Failure or Death: In the worst cases, systemic infection can cause organ failure, especially in animals with compromised immune systems, ultimately leading to death.

Who Is Most at Risk?

While any dog can develop Valley fever, certain populations are more vulnerable:

  • Puppies and Senior Dogs: Their immature or weakened immune systems are less able to contain the infection.
  • Immunocompromised Dogs: Dogs with existing health conditions or those on immunosuppressive medications are at increased risk for severe disease.
  • Dogs Living or Visiting Endemic Areas: Areas like Arizona, California, and Texas have high exposure risks due to soil conditions.

Diagnosis and Importance of Early Treatment

Because the symptoms of Valley fever often resemble other conditions like pneumonia or general illness, accurate diagnosis is crucial. Vets typically use:

  • Blood antibody tests
  • Chest X-rays
  • Cytology of affected tissues
  • Fungal cultures if required

Identifying the disease early and beginning treatment can prevent it from progressing into a disseminated and more life-threatening form.

Why Treatment Is Essential

Treating Valley fever usually involves long-term administration of antifungal medications such as fluconazole, itraconazole, or ketoconazole. Treatment may last 6–12 months or longer and often results in full recovery for cases limited to the lungs. Key reasons to seek treatment include:

  • Preventing dissemination to critical organs
  • Alleviating pain and improving quality of life
  • Reducing the risk of permanent damage or death
  • Increasing the likelihood of a full recovery

Supportive Care and Monitoring

In more severe cases, supportive care such as anti-inflammatories, pain relief, or IV fluids may be necessary. Vet monitoring is also important to track liver function and response to antifungal drugs, some of which can have side effects.

Prognosis With and Without Treatment

  • With Treatment: Over 90% of dogs with only lung involvement recover. Disseminated and neurologic cases are more serious but can still show improvement with aggressive therapy.
  • Without Treatment: The disease often worsens, with a higher risk of permanent damage, suffering, and eventual death, especially once major organs or the nervous system are affected.

Simple Prevention Tips

To reduce a dog’s risk of exposure in endemic areas:

  • Minimize contact with dusty or disturbed soil
  • Prevent digging in rodent holes or deserts
  • Keep dogs indoors during dust storms
  • Use grass or gravel to cover bare yard soil

A vaccine is currently under development, which may help reduce the impact of Valley fever in pets in the future.

Final Thoughts

Valley fever is a serious disease that requires timely diagnosis and consistent treatment. Without intervention, what begins as a mild respiratory illness can quickly progress into a debilitating and possibly fatal condition. If your dog lives in or visits areas where the infection is common and shows unexplained symptoms, prompt veterinary care could be the key to a successful recovery.

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