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What is pododermatitis caused by?

Pododermatitis is caused by various factors including infections, allergies, foreign bodies, hormonal imbalances, immune-mediated diseases, trauma, and anatomical issues.

Understanding the Causes of Pododermatitis in Dogs

Pododermatitis is a condition involving inflammation of the skin on a dog's paws or feet. It can affect various areas including the skin, interdigital spaces, pads, nail folds, and nails, leading to significant discomfort and mobility issues. Recognizing the causes of pododermatitis is key to identifying the right treatment and preventing recurrence.

Symptoms of Pododermatitis

  • Redness and swelling
  • Persistent licking or chewing of the feet
  • Hair loss and fur staining from saliva or yeast
  • Nodules, scabs, ulcers
  • Thickened, crusted pads
  • Changes in gait or lameness

Common Causes of Pododermatitis

There are several different causes of pododermatitis, which can often occur simultaneously:

1. Infectious Causes

  • Bacterial: Infections by Staphylococcus pseudintermedius, Streptococcus, or Pseudomonas are common.
  • Fungal: Yeast (e.g., Malassezia) and dermatophytes like ringworm can complicate the condition.
  • Parasitic: Demodex mites and hookworms can infect the paws, leading to inflammation and secondary infections.

2. Allergies

  • Environmental allergies (atopic dermatitis)
  • Food intolerance or allergies
  • Contact allergies, often from certain surfaces or chemicals

Allergic reactions can trigger intense itching, which prompts licking and chewing, aggravating the paws and leading to secondary infections.

3. Foreign Bodies

  • Grass awns, splinters, or thorns can penetrate the skin and cause localized inflammation, pain, and sometimes pus-draining lumps.

4. Hormonal Disorders

  • Hypothyroidism and Cushing’s disease can suppress the immune system, making it easier for secondary infections to take hold and slowing skin regeneration.

5. Immune-Mediated Diseases

  • Autoimmune conditions such as pemphigus foliaceus, lupus, and vasculitis can create blisters, ulcerations, and thickened, inflamed skin.

6. Conformational and Mechanical Issues

  • Dogs with splayed feet, short, bristly hair, or heavy body structure may develop chronic inflammation from abnormal weight distribution.

7. Tumors

  • Neoplasia such as squamous cell carcinoma, mast cell tumors, melanomas, and histiocytomas may cause nodules, ulcers, or persistent sores on the paws.

8. Trauma

  • Abrasions, burns, or friction from rough surfaces can initiate an inflammatory response and create entry points for infection.

9. Metabolic and Genetic Disorders

  • Conditions such as zinc-responsive dermatosis, inherited hyperkeratosis, and hepatocutaneous syndrome can affect paw health.

10. Behavioral Factors

  • Compulsive licking or chewing, such as from stress or boredom, can result in self-induced trauma and perpetuation of sores (as in acral lick granulomas).

Breed Predispositions

Certain breeds, including Bulldogs, Shar Peis, Boxers, German Shepherds, Retrievers, and Spaniels, are more likely to develop pododermatitis due to structural traits or genetic tendencies.

Diagnosis and Treatment

Veterinarians use various diagnostic tools to determine the underlying cause:

  • Skin scrapings for parasites
  • Cytology to evaluate infections
  • Cultures and biopsies for chronic or unclear cases
  • Hormonal panels and bloodwork
  • Allergy testing and diet trials

Treatment is tailored to the specific cause:

  • Antibiotics or antifungals for infections
  • Anti-inflammatory or immunomodulatory drugs for allergy or immune-related causes
  • Removal of foreign bodies and wound care
  • Hormonal therapy for endocrine disorders
  • Surgery or oncology treatments for tumors
  • Anti-parasitic agents as needed

Supportive and Preventative Care

  • Regular paw cleaning and drying
  • Antiseptic or Epsom salt soaks
  • Proper grooming and nail trimming
  • Monitoring for early signs of recurrence
  • Weight management and exercise modification
  • Avoiding allergens and harsh surfaces

Prognosis

Most cases respond well if the root cause is correctly identified and managed. However, chronic or autoimmune-related pododermatitis may require lifelong maintenance.

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