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What is steatitis in cats?

Steatitis, or yellow fat disease, is an inflammatory condition of fat tissue in cats caused mainly by a diet high in unsaturated fats and low in vitamin E. It leads to painful lumps under the skin, lethargy, and systemic illness.

Understanding Steatitis (Yellow Fat Disease) in Cats

Steatitis, also called yellow fat disease or pansteatitis, is a serious inflammatory disorder that affects the fat tissue of cats. While it might sound obscure, this condition can cause significant pain and health issues for your feline companion.

What Causes Steatitis?

The main culprit behind steatitis is a nutritional imbalance. Cats fed diets rich in unsaturated fatty acids—like those found in oily fish such as tuna, sardines, mackerel, herring, cod, or whitefish—are at risk if they don't get enough antioxidants, especially vitamin E. Without adequate vitamin E to protect their fat tissues from oxidative damage, cats develop inflammation and even necrosis (death) of fat cells.

  • Diets high in unsaturated fats without enough vitamin E
  • Feeding large amounts of pig's brain
  • Vitamin E deficiency for other reasons
  • Decreased antioxidant capacity due to illness
  • Infections (bacterial, fungal, mycobacterial)
  • Trauma or inflammatory disorders
  • Cancer or immune-mediated diseases
  • Rarely: toxins or reactions after injections

Some cases are idiopathic (meaning no clear cause is found), but unbalanced diets remain the top risk factor.

Symptoms: What to Watch For

Cats with steatitis often show clear signs of discomfort. The most common symptoms include:

  • Painful lumps or firm nodules under the skin (especially over the abdomen or back)
  • Lethargy and decreased activity—your cat may hide more than usual
  • Loss of appetite and weight loss
  • Reluctance to move or jump due to pain

Their fur may appear dull or greasy. In advanced cases, you might notice:

  • Fever and depression
  • Pain when touched or picked up
  • Nodules that ulcerate and ooze oily or bloody discharge
  • Alopecia (hair loss) over affected areas

Younger and overweight cats are particularly susceptible. Sometimes there are no outward symptoms; the disease is only discovered during surgery or after death by the distinctive yellowish, firm fat tissue.

How Is Steatitis Diagnosed?

Your veterinarian will start by reviewing your cat’s history and diet. A physical exam focuses on finding painful nodules and checking for systemic illness. Diagnostic steps often include:

  1. Bloodwork: Looks for signs of inflammation (like leukocytosis), anemia, and checks vitamin E levels.
  2. Fine-needle aspiration or biopsy: Confirms diagnosis by examining affected fat tissue under a microscope.

The hallmark findings are fat necrosis, ceroid pigment (a sign of lipid peroxidation), and inflammation dominated by macrophages and neutrophils. Imaging studies like ultrasound may help spot internal changes in fat density.

Treatment Options for Steatitis in Cats

The first step is immediate dietary correction—stop feeding excessive oily fish or unbalanced homemade foods. Switch your cat to a balanced commercial diet formulated specifically for felines. Vitamin E supplementation, usually as alpha-tocopherol, is essential; your vet will determine the right dose based on severity.

  • Corticosteroids may be prescribed to reduce pain, inflammation, and fever.
  • If infection is suspected, antibiotics or antifungals are added.

Your cat might need supportive care such as pain management medications, fluids for dehydration, and wound care if nodules have ulcerated. In severe cases where necrotic fatty tissue persists despite medical therapy, surgical removal may be necessary.

Prevention: Keeping Your Cat Safe From Steatitis

The best prevention is feeding your cat a nutritionally complete commercial diet—not homemade meals heavy on fish or animal brains. If you do supplement with fish oils for any reason, ensure proper vitamin E intake as well. Avoid giving large quantities of tuna or other oily fish long-term.

  • Avoid unbalanced homemade diets high in unsaturated fats.
  • Ensure adequate vitamin E if using supplements like fish oil.

Regular veterinary check-ups can catch early warning signs before they become serious problems.

The Prognosis: What Happens After Diagnosis?

If caught early and treated properly with dietary correction and supplementation, most cats recover within weeks. However, prognosis depends on how advanced the disease was at diagnosis and whether underlying causes persist. Some cats may relapse if poor dietary habits return; lifelong attention to nutrition helps prevent recurrence.

Main Takeaways About Steatitis in Cats

  • This disease results mainly from diets rich in unsaturated fats but low in antioxidants like vitamin E.
  • Painful lumps under the skin plus lethargy are common warning signs.

If you notice any behavioral changes—especially reluctance to move—or feel unusual lumps while petting your cat (particularly if they've been eating lots of oily fish), consult your veterinarian promptly. Early intervention makes all the difference for recovery and future well-being!

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