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What is the difference between advantage and Advantage Multi?

Advantage is a flea treatment, whereas Advantage Multi includes both flea control and protection against heartworms, mange, and intestinal parasites.

Understanding the Difference Between Advantage and Advantage Multi

When it comes to protecting your canine companion from pests and parasites, two names often come up: Advantage and Advantage Multi. Though they are often confused due to similar branding, these two products serve different purposes and are formulated with different active ingredients. In this article, we’ll explore their distinctions, benefits, and usage to help dog owners make an informed decision.

What Is Advantage?

Advantage is a topical flea treatment designed to kill adult fleas quickly and keep them from infesting your pet and home. Typically, it contains the active ingredient imidacloprid, which acts on the nervous system of fleas, eliminating them on contact.

Main Uses of Advantage:

  • Kills adult fleas on contact within 12 hours
  • Continues to kill fleas for up to 30 days
  • Helps control and prevent flea infestations

What Is Advantage Multi?

Advantage Multi for Dogs is a more comprehensive monthly topical solution that contains both imidacloprid (10%) and moxidectin (2.5%). This formulation extends its utility beyond just flea control, making it a broader-spectrum treatment for dogs.

Key Functions of Advantage Multi:

  • Prevents heartworm disease caused by Dirofilaria immitis
  • Treats circulating heartworm microfilariae in infected dogs
  • Kills adult fleas (Ctenocephalides felis)
  • Treats and controls sarcoptic mange (Sarcoptes scabiei)
  • Treats and controls intestinal parasites including hookworms, roundworms, and whipworms

How to Use Advantage Multi

Advantage Multi is applied topically once a month. Depending on your dog’s size, the application involves either one spot between the shoulder blades or multiple spots along the back.

Application Steps:

  1. Hold the applicator tube upright and remove the cap.
  2. Use the inverted cap to break the seal.
  3. Part the hair and apply directly to the skin.
  4. Prevent licking or contact with the application site for a designated time.

Safety and Side Effects

Advantage Multi is generally well-tolerated, though some dogs may experience mild reactions such as:
  • Itching at the application site
  • Damp hair appearance
  • Medicinal odor
More severe effects like vomiting, diarrhea, or incoordination can occur, especially in dogs with the MDR1 gene mutation.

Important Usage Considerations

  • Prescription required with current heartworm test
  • Do not use on dogs less than 7 weeks old or under 3 pounds
  • Not approved for use in cats
  • Avoid combining with other flea/heartworm medications

Comparing Advantage vs. Advantage Multi

Here’s a quick side-by-side comparison:
FeatureAdvantageAdvantage Multi
Active IngredientsImidaclopridImidacloprid + Moxidectin
Flea TreatmentYesYes
Heartworm PreventionNoYes
Intestinal ParasitesNoYes
Sarcoptic MangeNoYes
Prescription NeededNoYes

Storage and Environmental Resistance

Advantage Multi should be stored at room temperature between 39°F–77°F (4°C–25°C). Water immersion 90 minutes after application does not reduce heartworm efficacy. Bathing after four days has minimal effect on flea protection, but frequent washing may lower effectiveness.

Conclusion

While both Advantage and Advantage Multi offer effective flea control, Advantage Multi provides a much broader spectrum of protection. It is ideal for owners looking for an all-in-one solution that includes heartworm prevention, treatment of mange, and control of intestinal parasites. Always consult your veterinarian to determine which product is most appropriate for your dog's specific needs.

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