Recognizing the Symptoms of Cushing's Disease in Dogs
Cushing’s disease, also known as hyperadrenocorticism, is a hormonal disorder caused by an overproduction of cortisol. It commonly affects middle-aged and older dogs and develops gradually, making early detection challenging. Understanding its symptoms is crucial for ensuring timely diagnosis and management.
Understanding Cortisol’s Role
Cortisol plays a vital role in a dog’s ability to respond to stress, fight infections, regulate metabolism, and maintain body weight. When present in excess, it disrupts these body processes and leads to a range of health issues.
Main Types and Causes of Cushing’s Disease
- Pituitary-dependent Cushing’s: Caused by a benign tumor on the pituitary gland prompting cortisol overproduction (about 80–90% of cases).
- Adrenal-dependent Cushing’s: Involves a tumor on one of the adrenal glands.
- Iatrogenic Cushing’s: Results from prolonged corticosteroid use.
Common Symptoms of Cushing’s Disease in Dogs
Signs develop slowly and can often be mistaken for normal aging. Owners should look out for the following symptoms:
- Increased thirst and urination (polydipsia and polyuria)
- Increased appetite (polyphagia)
- Pot-bellied or swollen abdomen
- Hair loss or slow regrowth, especially on the body
- Thin, fragile skin with delayed wound healing
- Excessive panting
- Muscle weakness or general lethargy
- Dark patches on the skin and blackheads
- Frequent urination or house soiling in previously trained dogs
- Weight gain or abnormal fat distribution
- Recurrent skin infections
Recognizing Subtle Early Signs
Symptoms may appear mild initially. Some subtle indicators include:
- Lethargy or reduced activity levels
- Subtle weight changes or enlarged belly
- Increased respirations or panting at rest
Breeds at Risk
Certain breeds are more predisposed to Cushing’s disease, including:
- Poodles
- Dachshunds
- Yorkshire Terriers
- Boston Terriers and other small breeds
Why Timely Recognition Matters
Untreated Cushing’s disease can lead to complications like diabetes mellitus, kidney damage, high blood pressure, infections, and even death. Timely veterinary intervention minimizes these risks and enhances your dog’s quality of life.
What to Do If You Notice Symptoms
If your dog shows any of the signs listed above, consult your veterinarian. A comprehensive evaluation, including bloodwork, urine analysis, and specialized hormone tests (e.g., ACTH stimulation or low-dose dexamethasone suppression test), may be recommended.
Conclusion
The symptoms of Cushing’s disease in dogs are diverse and develop slowly. Paying attention to increased thirst, appetite, pot-bellied appearance, and changes in behavior or skin can help you catch the disease early. With veterinary support, dogs with Cushing’s can lead a happy, managed life.





