Is Dramamine Safe for Dogs? What Pet Owners Should Know
If you’re planning a trip with your canine companion and are concerned about motion sickness, you may be wondering whether Dramamine is a safe option for your dog. Dramamine, also known by its generic name dimenhydrinate, is an antihistamine commonly used to treat and prevent motion sickness. Let’s explore how safe and effective it is for dogs.
What is Dramamine?
Dramamine is an over-the-counter medication primarily marketed for humans. It works by blocking signals in the brain that trigger nausea and vomiting. It is available in several forms:
- Regular tablets
- Chewable tablets
- Oral liquid
There are no veterinary-specific versions of Dramamine; only human-formulated ones are used for dogs under veterinary guidance.
Safe Use of Dramamine in Dogs
Even though dimenhydrinate is FDA-approved for humans, veterinarians often prescribe it to dogs for off-label use in treating motion sickness and vestibular disease. It is considered effective for managing symptoms such as:
- Nausea
- Vomiting
- Excessive drooling
- Whining or restlessness
- Panting
- Discomfort during travel
This makes Dramamine a useful option for road trips, air travel, or boat rides with your dog.
Recommended Dosage
The typical dosage of Dramamine for dogs is 2 to 4 mg per pound of body weight, administered every 8 hours. For example:
- A small dog might receive 25 mg
- A large dog might receive 50 mg
It’s crucial to consult your veterinarian for the appropriate dose, especially for dogs weighing less than 6 pounds.
How to Administer Dramamine
Dramamine can be administered with or without food, although giving it with a small snack may reduce the risk of stomach upset. For travel, give the dose 30 to 60 minutes before departure to maximize benefits. The effects usually last up to 8 hours.
Important Safety Considerations
Only use Dramamine that contains dimenhydrinate as the only active ingredient. Avoid:
- Combination products
- “Non-drowsy” formulas (which may contain ginger or other agents)
Human drugs should always be administered under veterinary supervision to ensure they are safe for your individual pet.
Potential Side Effects
While most dogs tolerate Dramamine well, possible side effects include:
- Drowsiness or sedation
- Dry mouth or increased thirst
- Loss of appetite
- Vomiting or diarrhea
- Difficulty urinating
- Rare cases of hyperactivity or seizures (with overdose)
Watch for signs of an allergic reaction such as facial swelling, hives, or difficulty breathing, and seek immediate veterinary attention if they occur.
Health Conditions That Require Caution
Dramamine should be used cautiously in dogs with:
- Glaucoma
- Seizure disorders
- Overactive thyroid
- Heart disease
- High blood pressure
- Urinary or GI blockages
- Asthma or respiratory issues
It should not be given to:
- Dogs allergic to antihistamines
- Neonatal puppies
- Dogs undergoing allergy skin testing
For pregnant and elderly dogs, use may be appropriate but requires veterinary oversight.
Drug Interactions
Dramamine can interact with other medications, including:
- Other antihistamines
- Sedatives or muscle relaxants
- Benzodiazepines (e.g., diazepam)
- Opioid pain relievers
- Antidepressants
- Antiseizure medications
- Anticholinergic drugs
Always inform your veterinarian about all medications, supplements, or natural remedies your dog is taking.
Alternatives to Dramamine
Not all dogs respond well to Dramamine. In those cases, alternatives include:
- Other antihistamines like cetirizine, diphenhydramine (Benadryl), or chlorphenamine
- Prescription drugs like maropitant citrate (Cerenia), trazodone, or gabapentin
- Non-drug options such as desensitization training, calming wraps, or herbal remedies like ginger
What to Do If You Miss a Dose
If you miss giving your dog a dose of Dramamine, administer it as soon as you remember. However, do not double up on the next dose. Store the medication at room temperature and protect liquids from freezing.
A Final Word of Caution
Before giving your dog Dramamine or any new medication, always consult your veterinarian. Careful monitoring during its use is essential, especially if your dog has pre-existing health conditions or is on other treatments. Dramamine should be considered part of a broader strategy for managing travel anxiety and motion sickness in dogs.
Conclusion
Dramamine can be a safe and effective solution for canine motion sickness when used responsibly. Choose the plain formulation containing only dimenhydrinate, and closely follow dosing recommendations from your vet. With the right precautions, your furry friend can enjoy a more comfortable and anxiety-free journey.





