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What is the best thing to give a horse for colic?

Banamine (flunixin meglumine) is the most commonly recommended medication by veterinarians for managing pain and inflammation in colic-affected horses.

What to Give a Horse for Colic: Understanding the Role of Banamine

When a horse shows signs of colic, which refers to abdominal pain with varying causes and severity, swift and appropriate action is essential. While colic can sometimes resolve on its own, many cases require veterinary intervention and medication to manage pain and prevent complications. One of the most common treatments veterinarians recommend in such situations is Banamine, also known by its generic name, flunixin meglumine.

What is Banamine?

Banamine is a non-steroidal anti-inflammatory drug (NSAID) that has been used in equine veterinary medicine for several decades. It works by inhibiting enzymes known as cyclooxygenases (COX), specifically blocking COX-1 and COX-2. These enzymes are responsible for producing prostaglandins, which mediate inflammation, pain, and fever.

Why Use Banamine for Colic?

Banamine is particularly effective for visceral pain, such as that caused by gastrointestinal discomfort during colic episodes. Its properties also make it beneficial in cases of
  • Musculoskeletal disorders
  • Lameness
  • Soft tissue injuries
  • Eye inflammation (uveitis or corneal ulcers)
  • Cellulitis
  • Post-operative pain
  • Fever
In severe colic cases, Banamine's anti-endotoxic effects are crucial. Endotoxemia, the presence of bacterial toxins in the bloodstream, is a serious condition often associated with advanced colic and gastrointestinal infections. Banamine helps manage both the pain and systemic effects of these toxins.

How is Banamine Administered?

Banamine is available in multiple forms:
  • Injectable solution (commonly administered intravenously by veterinarians)
  • Oral paste (safe and convenient for horse owners)
  • Oral granules
While injectable formulas are fast-acting, veterinarians advise against horse owners giving IV injections themselves due to the risk of severe complications such as tissue necrosis or accidental intra-arterial injection. Though labeled for intramuscular injection, IM administration is not recommended due to the risk of clostridial myositis, a potentially fatal muscle infection. Symptoms include swelling, gas formation under the skin, pain, and systemic illness. Any IM injection should be monitored closely.

What is the Correct Dosage?

The standard dosage for Banamine in horses is typically 1.1 mg/kg of body weight (approximately 0.5 mg/lb), and it should not be given more frequently than every 12 hours. For injectable Banamine, this works out to 1 mL per 100 lbs of body weight. Oral dosages vary depending on the horse’s specific needs and should be calculated with veterinary guidance. Important: Never exceed the recommended dose, and do not combine Banamine with other NSAIDs, as this increases the risk of severe side effects.

What Are the Risks and Side Effects?

Though effective, Banamine is not without risks. Potential side effects include:
  • Gastric and colonic ulcers
  • Right dorsal colitis
  • Kidney damage, especially in dehydrated horses
  • Diarrhea and gastrointestinal upset
  • Local injection site reactions
  • Rare anaphylactoid reactions when administered IV
Foals are particularly sensitive to NSAIDs and may clear the drug more slowly, increasing the risk of side effects. Horses with preexisting kidney conditions or those that are dehydrated require close monitoring.

Best Practices for Using Banamine

To minimize risk and enhance effectiveness,
  • Use oral forms for home administration
  • Have IV injections performed by a licensed veterinarian
  • Avoid IM injections
  • Monitor for adverse effects
  • Ensure the horse is well-hydrated
For horses on long-term Banamine treatment or those predisposed to developing ulcers, your vet may recommend gastrointestinal protectants.

How Banamine Compares to Bute

Another popular NSAID in horse care is phenylbutazone (bute), which is typically used for orthopedic pain. In contrast, Banamine is preferred for colic and systemic fever. Both NSAIDs carry similar risks and require careful dosing under veterinary supervision.

Veterinary Oversight is Crucial

While Banamine can offer rapid symptom relief, it can also mask the severity of colic, preventing timely treatment of life-threatening conditions such as twisted intestines or impactions. Always follow up with a veterinarian if your horse shows signs of:
  • Severe or persistent pain
  • Depression or lethargy
  • Reduced gut sounds or lack of bowel movements
  • Swelling at the injection site
  • Discolored gums or signs of shock

Conclusion

Banamine remains the gold standard for managing pain and inflammation in colic-affected horses. However, due to its potential complications and the complex nature of colic, always involve a veterinarian in diagnosis and treatment. Administer Banamine in its safest forms, avoid overuse, and observe your horse closely to ensure the best outcome.

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