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What causes an iris bombe?

Iris bombe is caused by complete posterior synechiae, where the iris adheres 360 degrees to the lens capsule, blocking aqueous humor flow and increasing intraocular pressure.

Understanding Iris Bombe in Cats: Causes, Symptoms, and Treatment

Iris bombe is a critical ocular condition observed in cats and other animals, often stemming from severe inflammation within the eye. This article provides a comprehensive overview of what causes this condition, how it manifests, and the treatment options available to pet owners aiming to preserve their cat’s vision.

What is Iris Bombe?

Iris bombe occurs when the iris—the colored tissue surrounding the pupil—adheres in a full 360-degree ring to the lens capsule, forming what is known as posterior synechiae. This complete attachment obstructs the normal flow of aqueous humor, the fluid inside the eye, resulting in increased intraocular pressure. The pressure forces the iris to bulge forward into the anterior chamber, giving the eye a distinctive, ballooned appearance.

Primary Causes of Iris Bombe

Iris bombe usually arises from intraocular inflammation known as uveitis. Several underlying factors can trigger this inflammation, leading to synechiae formation:
  • Trauma – Physical injuries from fights or accidents.
  • Chronic Infections – Persistent bacterial or viral infections.
  • Foreign Body Injury – Objects entering the eye causing severe inflammation.
  • Corneal Ulcers – Deep, infected wounds on the cornea.
  • Hyphema – Blood pooling in the anterior chamber of the eye.
  • Certain Tumors – Neoplasia affecting internal eye structures.
  • Congenital Anomalies – Rare, but not impossible in some breeds.
Feline-specific infections associated with uveitis and iris bombe include:
  • Feline Immunodeficiency Virus (FIV)
  • Feline Leukemia Virus (FeLV)
  • Feline Infectious Peritonitis (FIP)
  • Toxoplasmosis

Clinical Signs of Iris Bombe

Owners should be vigilant for these symptoms:
  • Bulging of the iris into the anterior chamber
  • Squinting or eye discomfort (blepharospasm)
  • Redness and visible inflammation
  • Cloudy lens appearance or corneal opacities
  • Corneal ulcers or scars
  • Excessive tearing or discharge
  • Altered vision including reduced brightness response or blindness
  • Darkening or distortion of the iris color or shape
  • Irregular-shaped pupil and reduced reaction to light
  • Behavioral changes like lethargy or hiding

Diagnosis Procedures

A veterinarian will perform a detailed ophthalmic examination composed of:
  • Slit-lamp biomicroscopy – Assessing the anterior eye structures
  • Fluorescein staining – Evaluating corneal integrity
  • Tonometry – Measuring eye pressure to detect glaucoma
  • Gonioscopy – Examining the drainage angle of the eye
  • Ophthalmoscopy – Viewing the retina and optic nerve

Treatment Options

Early and aggressive treatment is critical to enhance outcomes. Efforts typically include:
  • Anti-inflammatory medications like corticosteroids or NSAIDs
  • Mydriatics (pupil dilators) to break fresh adhesions
  • IOP-lowering agents such as carbonic anhydrase inhibitors or beta-blockers
  • Surgery for long-standing or severe cases (e.g., synechiolysis, laser iridotomy)
  • Antibiotics or antifungals if an infection is identified
  • Treatment of systemic illness contributing to eye inflammation
  • Frequent follow-up exams to monitor pressure and response

Prognosis

Prognosis depends on the following:
  • The extent of adhesions and iris bulging
  • Presence or absence of secondary glaucoma
  • Speed and effectiveness of veterinary intervention
In cases of chronic and severe inflammation, the prognosis remains guarded despite treatment. However, early intervention offers the best chance of retaining some degree of vision.

Prevention

Though not always preventable, you can reduce a cat’s risk by:
  • Promptly treating eye injuries and infections
  • Limiting exposure to environments where trauma might occur
  • Scheduling regular veterinary eye exams, especially for at-risk cats
  • Vaccinating against FeLV and FIV
  • Maintaining cleanliness to lower infection risk
  • Observing your cat’s eye behavior for early signs of discomfort

Is Iris Bombe Contagious?

No, iris bombe itself is not contagious, but the infections resulting in uveitis might be. Isolate infected cats and consult your veterinarian.

Similar Conditions in Other Species

Dogs and other animals can also experience iris bombe, typically associated with chronic intraocular inflammation. The prognosis in these cases is similar—careful management is required to control pressure and adhesions.

Conclusion

Iris bombe is an ocular emergency that requires prompt attention. Recognizing the signs and securing timely veterinary care can make the difference between preserved vision and blindness. Pet owners should prioritize regular eye examinations and immediate consultation when abnormalities arise.

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