Understanding the Difference Between Advantage and Advantage II for Cats
For pet owners, protecting cats from fleas is a top priority. Two popular flea treatments on the market are
Advantage and
Advantage II. While they may sound similar, there are key differences that impact their efficacy, ingredients, and mode of action. This guide aims to clarify those differences, so you can make an informed choice for your cat's health.
What is Advantage for Cats?
Advantage was one of the earlier topical flea treatments developed for cats. Its sole
active ingredient is imidacloprid, which targets and kills adult fleas on contact. This feature means fleas don't have to bite your cat to die, reducing the risk of flea-related irritation and diseases. The product is applied monthly and absorbed through the skin, effectively killing adult fleas within 12 hours.
Introducing Advantage II for Cats
Advantage II is an upgraded version of the original formula.
In addition to imidacloprid, Advantage II also contains
pyriproxyfen, an insect growth regulator (IGR). This second ingredient targets the
entire flea life cycle by preventing flea eggs and larvae from maturing into adult fleas.
- Imidacloprid (9.10%) – Kills adult fleas by attacking their nervous system.
- Pyriproxyfen (0.46%) – Prevents flea eggs and larvae from developing, stopping the flea life cycle.
This dual-action makes Advantage II more effective at
controlling infestations and preventing re-infestations.
Weight Categories and Application
Advantage II is tailored to cats of different weights:
- 2–5 lbs – Turquoise pack
- 5–9 lbs – Orange pack
- Over 9 lbs – Purple pack
The application involves:
- Holding the applicator upright and removing the cap.
- Using the reversed cap to break the seal.
- Parting the fur at the base of the skull and applying the contents onto the skin.
Application at the base of the neck minimizes chances of ingestion. The treatment is
waterproof after 24 hours and fragrance-free.
Speed and Duration of Effectiveness
Advantage II starts killing adult fleas within
12 hours and eliminates re-infesting fleas within 2 hours. It offers up to
30 days of continuous protection against fleas.
In severe infestations, retreatment may be done sooner, though not more often than:
- Once every 14 days for kittens
- Once every 7 days for small and large cats
After flea control is established, resume the regular monthly schedule.
Health and Safety Considerations
Advantage II is suitable for cats and kittens aged
8 weeks and older and above the minimum weight. It is
veterinarian-recommended and does not require a prescription. Side effects may include temporary salivation if licked shortly after application. Watch for
skin irritation or gastrointestinal upset, especially in elderly, pregnant, or medicated cats. Store the product in a cool, dry place out of reach of children and pets.
Benefits of Advantage II Over Original Advantage
Advantage II offers several benefits over the original formula:
- Targets the full flea life cycle
- Prevents development of flea eggs and larvae
- Reduces risk of re-infestation
- Provides faster kill rate for newly arriving fleas
- Veterinarian-recommended without need for a prescription
Why Breaking the Flea Life Cycle Matters
By eliminating eggs, larvae, and adult fleas, Advantage II helps prevent long-term infestations. Fleas can cause more than just itchiness—they may lead to
tapeworms, flea bite anemia, and flea allergy dermatitis. A product like Advantage II that interrupts flea development is more effective for both immediate relief and long-term prevention.
Conclusion
While both Advantage and Advantage II are effective topical flea treatments,
Advantage II offers superior protection by incorporating an insect growth regulator that disrupts flea reproduction. This makes it a better choice for preventing full-blown infestations and keeping your cat healthy year-round.
