Understanding Why Your Dog May Need a Biopsy
As a pet parent, it's natural to feel concerned when a veterinarian recommends a biopsy for your dog. It's a word many associate with serious illness, but in veterinary medicine, a biopsy is a common and vital diagnostic tool. It involves removing a small piece of tissue to be evaluated under a microscope by a veterinary pathologist. This procedure can provide detailed insight into what is causing a disease and help determine the best treatment options.
What Is a Biopsy?
A biopsy is a procedure where a sample of tissue is collected from a specific organ or lesion on your dog's body. The goal is to obtain cells or tissue that can help identify the nature of a condition—whether it's inflammatory, infectious, autoimmune, degenerative, or cancerous.
Common Reasons for a Dog Biopsy
- To diagnose suspicious skin growths or tumors
- To distinguish between benign and malignant lesions
- To investigate chronic or unusual skin changes
- To identify infections, autoimmune disorders, or inflammatory diseases
- To determine the best treatment route and prognosis
Skin biopsies are especially frequent in dogs, often performed on non-healing wounds, unusual textures or colors, and rapidly growing masses. If a lesion is not responding to treatment, a biopsy provides key information.
Types of Biopsies Used in Dogs
There are several biopsy techniques depending on the tissue, location, and clinical suspicion:
- Fine Needle Aspiration (FNA): The least invasive method, using a needle to collect cells. It’s quick but may yield less information due to limited sample size.
- Punch Biopsy: A circular blade collects a full-thickness skin sample. Ideal for dermatologic investigations, typically performed in multiple locations.
- Wedge Biopsy: A "V" shaped deep tissue cut includes both abnormal and normal tissue. Useful for evaluating lesion margins.
- Shave Biopsy: Removes superficial skin layers. Best for surface-confined abnormalities.
- Excisional Biopsy: The entire abnormality is removed, often used for small and resectable masses.
- Jamshidi Needle Biopsy: A special needle collects bone core samples. Minimally invasive with fewer complications than surgical methods.
- Surgical Biopsy: Includes incisional biopsies or more extensive surgical excisions under general anesthesia.
Diagnostic Yield and Process
Once tissue is collected, it's placed in formalin and sent to a laboratory. There, it’s processed, stained, and examined microscopically. Sometimes advanced techniques like immunohistochemistry are used to distinguish challenging cell types or identify the origin of cancerous tissue.
Each report details the specimen’s appearance, suspected diagnosis, and key metrics like cell differentiation and mitotic index, which help guide further treatment like surgery, chemotherapy, or radiation.
Risks and Recovery
While generally safe, biopsies do carry some risks:
- Bleeding
- Pain
- Infection
- Delayed healing
- Fracture (in rare cases during bone biopsies)
Most dogs recover well, especially after less invasive biopsies. Post-procedure, your vet will advise on pain management, rest, and signs of infection to watch for. Stitches are typically removed after 10–14 days, and lab results return within 1–2 weeks.
When Might a Biopsy Be Skipped?
In some cases, if the treatment plan won’t change regardless of biopsy results or if the lesion is small and easily excised, vets may recommend skipping a preliminary biopsy and opting for complete removal. However, in most cases, having a clear diagnosis before major intervention is critical.
Making the Decision Together
Deciding to biopsy involves discussing the lesion’s location, your dog’s overall health, and the likelihood of diagnosis affecting treatment. While a biopsy may not always give a conclusive answer, it often offers the highest yield in understanding a disease process and ensuring appropriate future care.
In summary, biopsies are a cornerstone of veterinary diagnostics, helping to distinguish between various diseases and guiding customized, effective treatment plans for your dog. Always consult your vet thoroughly about the goals and implications of performing a biopsy.





