Understanding Pain and Degenerative Myelopathy in Dogs
Degenerative myelopathy (DM) is a progressive neurological disease that affects the spinal cord of dogs, leading to a gradual loss of coordination and mobility — usually starting in the hind limbs. Despite its severe physical impact, one of the distinguishing features of DM is that it is generally considered a non-painful condition. This article explores the nature of DM in dogs, how it manifests, and how it affects their comfort and quality of life.
What is Degenerative Myelopathy?
DM is a non-painful, neurodegenerative disease that gradually affects the spinal cord. It most often appears in dogs between 4 and 14 years of age and is linked to a genetic mutation in the SOD1 gene. Over 40 breeds are documented as being at risk, including:
- German Shepherds
- Pembroke and Cardigan Welsh Corgis
- Boxers
- Golden Retrievers
- Bernese Mountain Dogs
- Chesapeake Bay Retrievers
- Siberian Huskies
- Poodles and Pugs
Although dogs with two copies of the mutated gene are most at risk, not all develop DM, suggesting that other genetic or environmental factors may be involved.
Clinical Signs of DM
Symptoms usually start subtly and worsen over time:
- Loss of coordination in the hind limbs
- Scraping or dragging paws
- Muscle atrophy (loss of muscle mass)
- Difficulty rising or standing
- Crossing of hind legs or swaying gait
- Urinary and fecal incontinence in later stages
As the disease progresses, dogs may eventually become paraplegic and lose respiratory muscle function.
Does DM Cause Pain?
Most dogs with DM do not experience pain as a direct symptom of the disease. The degeneration in the spinal cord usually impairs movement without stimulating pain receptors. That said, affected dogs may show signs of anxiety or irritability due to restricted mobility and loss of independence.
However, DM often occurs alongside other conditions that do cause discomfort, such as:
- Osteoarthritis
- Hip dysplasia
- Spinal disc issues
It’s important for pet owners to distinguish whether signs of distress are due to these concurrent conditions as opposed to DM itself.
Diagnosis of DM
DM is diagnosed by excluding other possible causes of similar symptoms. Diagnostic procedures may include:
- Radiographs (X-rays)
- CT or MRI scans
- Myelography
- Cerebrospinal fluid analysis
- Genetic testing for the SOD1 mutation
Definitive diagnosis can only be made post-mortem through histopathological examination of spinal tissue.
Managing Life with DM
There is currently no cure for degenerative myelopathy. Treatment revolves around slowing disease progression and maintaining quality of life. Important aspects of care include:
- Physical therapy and hydrotherapy: Help preserve muscle mass and coordination
- Mobility aids: Carts, harnesses, ramps, booties
- Weight management: Helps reduce strain on joints and muscles
- Nursing care: Preventing bedsores, keeping areas clean of urine or feces
- Monitoring for secondary conditions: Infections or injurious pressure points
Some dogs may benefit from regular vet visits to manage associated conditions like arthritis that can cause pain and discomfort — even if DM itself does not.
Prognosis and Quality of Life
The disease is unfortunately progressive and ultimately fatal. Most dogs lose the ability to walk within 6–12 months of diagnosis. Advanced cases may require humane euthanasia within 1–2 years, depending on the dog’s mobility and quality of life. Rarely, dogs with intensive support and therapy can live longer while maintaining good quality of life.
The focus should be on maintaining dignity and comfort rather than prolonging life at any cost. Working closely with veterinarians and neurologists helps tailor an individualized care approach that best supports the dog’s needs.
Breeding Considerations
Genetic screening in high-risk breeds can help lower the incidence of DM. Dogs identified as carriers or at-risk should be carefully considered before breeding to prevent passing on the mutation.
Conclusion
Degenerative myelopathy in dogs is not a painful condition by itself, but pet owners should be vigilant for overlapping issues like joint disease that may cause discomfort. A multifaceted care plan that includes physical therapy, pain management for comorbid conditions, and mobility support can significantly improve an affected dog’s quality of life during its progression.





