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What is the best thing to give a horse for colic?

Banamine (flunixin meglumine) is commonly used by veterinarians to relieve pain and inflammation in horses with colic, but it should only be administered under veterinary guidance.

What to Give a Horse for Colic: Understanding the Use of Banamine

Colic in horses is a potentially life-threatening condition that requires quick intervention. Recognizing the signs early and knowing what to do can make all the difference. Among veterinarians’ tools to manage and assess colic symptoms is a drug known as Banamine, or flunixin meglumine, a non-steroidal anti-inflammatory drug (NSAID) known for its effectiveness in managing colic-related pain in horses. This article offers an in-depth look at Banamine, focusing on proper use, dosage, risks, and important safety considerations.

What Is Banamine?

Banamine is a non-selective NSAID that works by inhibiting COX-1 and COX-2 enzymes responsible for the production of prostaglandins. These compounds play a key role in pain, inflammation, and fever. While the drug’s effects help alleviate colic symptoms, overuse or improper administration can lead to serious side effects.

Banamine Uses in Horses

In veterinary practice, Banamine is employed for a range of equine conditions, including:

  • Colic-related visceral pain
  • Soft tissue injuries and lameness
  • Musculoskeletal disorders
  • Post-surgical pain
  • Fever control
  • Eye pain due to conditions like corneal ulcers
  • Cellulitis and endotoxemia

Forms of Banamine

Banamine comes in multiple formulations to suit different treatment needs:

  • Injectable solution – Typically administered intravenously (IV) by veterinarians
  • Oral paste – Suitable for at-home administration
  • Granules – Another oral option for easier dosing over feed

Note: Transdermal Banamine is approved for cattle but not for horses.

How to Administer Banamine Safely

Correct administration is essential for Banamine’s safety and effectiveness. Here are best practices:

  • Oral administration is the safest method for horse owners
  • IV administration provides faster relief but must be done by a veterinarian
  • IM injections are not recommended due to the risk of deadly infections such as clostridial myositis

Risks of IM Administration

Injecting Banamine into muscle tissue can introduce Clostridium bacteria, which may lead to clostridial myositis—a serious, sometimes fatal, condition. Symptoms include:

  • Severe swelling at the injection site
  • Pain and heat in the affected area
  • Systemic illness symptoms like depression
  • Gas pockets under the skin

Emergency veterinary treatment is necessary if these symptoms appear.

Correct Dosage

The recommended dose for Banamine is 1.1 mg/kg (about 0.5 mg/lb) of body weight, not to exceed every 12 hours. Injectable Banamine is typically given at 1 mL per 100 lbs, adjusted for the horse’s weight and condition. Duration of administration should generally not exceed 5–7 days without veterinary guidance.

Special Populations and Drug Interactions

Foals, dehydrated horses, and those with pre-existing kidney issues are more susceptible to NSAID side effects. It’s crucial not to:

  • Combine Banamine with other NSAIDs
  • Exceed prescribed dosing intervals
  • Give to horses with compromised hydration or kidney function without professional advice

Side Effects to Watch For

  • Gastric or colonic ulcers, including right dorsal colitis
  • Kidney damage (renal papillary necrosis)
  • Diarrhea or digestive upset
  • Local reactions at injection sites
  • Rare allergic or anaphylactic reactions (especially with IV use)

Monitoring and Veterinary Involvement

Always consult a veterinarian before administering Banamine. While the drug masks symptoms effectively, it can hide underlying issues that may worsen. Monitor your horse for:

  • Changes in behavior
  • Swelling or pain at injection sites
  • Unusual urination patterns
  • Signs of gastrointestinal distress

Banamine vs. Phenylbutazone

While Banamine is ideal for visceral pain like that associated with colic, phenylbutazone (bute) is more effective for musculoskeletal disorders. Both share similar risks, especially regarding gut and kidney health, and should never be combined.

Conclusion

Banamine is generally considered the best medication to give a horse for colic, provided it’s administered correctly and under guidance. Owners should prefer oral routes, never inject IM, and seek immediate veterinary help if symptoms persist. Understanding the medications your horse may receive ensures safer, faster recovery and better overall care in a time-critical situation like colic.

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