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Aujeszky Disease in Dogs: A Fatal Viral Threat

Aujeszky disease, also known as pseudorabies, is a severe and nearly always fatal viral infection in dogs caused by Suid herpesvirus 1 (SHV-1). Though the primary host is swine, the virus can infect a wide range of mammals including dogs, cats, cattle, sheep, and wild animals. This article delves into how this disease affects dogs, modes of transmission, clinical presentation, diagnosis, and prevention.

What Causes Aujeszky Disease?

The infection is caused by Suid herpesvirus 1, a member of the Alphaherpesvirinae subfamily. While pigs serve as the natural reservoir of the virus and can survive the disease in a latent state, other species, including dogs, face a grim prognosis.

How Dogs Become Infected

Dogs generally contract the virus through:
  • Ingestion of raw pork or offal from infected swine or wild boar
  • Contact with contaminated environments (grass, soil, feed)
It is important to note that dog-to-dog transmission does not occur.

Incubation and Clinical Signs

The incubation period ranges from 2 to 10 days. Once symptoms appear, the disease advances rapidly. Common clinical symptoms include:
  • Sudden behavioral changes
  • Seizures
  • Muscle tremors and loss of coordination
  • Excessive salivation
  • Intense localized pruritus ("mad itch")
  • Severe itching of the head and face leading to self-mutilation
  • Jaw and pharyngeal paralysis
  • Vomiting and diarrhea
  • Respiratory distress
This intense pruritus and neurological deterioration usually lead to death within 24 to 48 hours after symptom onset.

Diagnostic Methods

Given the rapid progression, diagnosis often occurs postmortem. Diagnostic tools include:
  • Polymerase Chain Reaction (PCR) to detect viral DNA
  • Virus isolation from tissues
  • Histopathological examination showing encephalomyelitis and inclusion bodies
  • Immunohistochemistry
  • Serological assays (primarily for pigs, not dogs)
Differential diagnoses include rabies, canine distemper, and poisoning.

Pathological Findings in Dogs

Studies in infected dogs show:
  • Brainstem encephalitis
  • Ganglioneuritis and systemic hemorrhages
  • Myocardial necrosis and cardiac lesions
  • Pulmonary edema and respiratory complications
  • Elevated cardiac troponin-I levels indicating heart damage
The virus appears to concentrate in the central and peripheral nervous systems.

Is There Treatment or a Vaccine?

Unfortunately, no treatment or vaccine exists for dogs. Supportive care is only palliative, focusing solely on comfort and symptom relief. This emphasizes the critical importance of prevention.

Preventing Aujeszky Disease in Dogs

Key prevention strategies include:
  • Never feeding dogs raw pork or wild boar meat
  • Supervising hunting dogs during excursions
  • Decontaminating dogs after exposure to swine or wild boar
  • Observing strict biosecurity for dogs on pig farms
Owners of hunting or farm dogs should be particularly cautious.

Virus Survival and Environmental Risks

Suid herpesvirus 1 can live for days in environmental elements like:
  • Grass and soil
  • Animal feed
  • Contaminated equipment
Thus, even without direct contact with an infected animal, dogs can get exposed.

Global Distribution and Epidemiology

The virus is endemic in several regions including:
  • Europe
  • Asia
  • Americas
Wild boars and feral pigs play a significant role in the sylvatic cycle, maintaining the disease in nature. Vaccination campaigns and biosecurity in swine farming are key to containment.

Conclusion

Aujeszky disease poses a lethal threat to dogs, especially those in rural or hunting environments. Since there is no treatment or vaccine, awareness and prevention are the only effective measures. Dog owners must stay vigilant and avoid any potential exposure routes to protect their pets from this fatal viral disease.

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