Understanding the Key Differences Between Bravecto and Credelio
Choosing the right flea and tick prevention for your pet can be overwhelming given the range of products on the market. Two popular prescription treatments are Bravecto and Credelio. While both are effective options, they differ significantly in terms of active ingredients, dosage schedules, and spectrum of protection. In this article, we dive deep into what sets these medications apart and help pet owners make an informed choice for their feline companion.
Credelio: Monthly Protection for Cats
Credelio (lotilaner) is a flavored chewable tablet used in cats and kittens to treat and prevent flea infestations and control certain tick species.
- Active Ingredient: Lotilaner, an isoxazoline class compound.
- Dosage Frequency: Administered once a month.
- Target Species: Cats and kittens over 8 weeks old and weighing at least 2 pounds (for fleas), and over 6 months old for tick control.
- Flea Protection: Starts killing fleas within 6 hours; 100% efficacy at 24 hours sustained for one month.
- Tick Protection: Effective primarily against black-legged (deer) ticks; over 97% effectiveness within 72 hours that lasts up to 31 days.
- Administration: Given with food for optimal absorption.
- Tablet Sizes: 12 mg (2–4 lb cats) and 48 mg (4.1–17 lb cats); appropriate combinations for heavier cats.
Credelio is well-tolerated with minor side effects such as vomiting, weight loss, or diarrhea. Rare neurological effects have been reported, especially in animals with pre-existing seizure conditions.
How Does Bravecto Compare?
Though not detailed in this specific source text, Bravecto in general is renowned for its longer duration of action. Unlike Credelio, which needs monthly dosing, Bravecto typically offers up to 12 weeks of protection with a single dose. Bravecto for cats is also an oral treatment and contains fluralaner, another isoxazoline compound.
- Longer Duration: Protects for up to 12 weeks.
- Active Ingredient: Fluralaner.
- Spectrum: Typically covers multiple flea and tick species.
Due to its longer-acting protection, Bravecto might be preferred by owners seeking less frequent dosing, while Credelio offers consistent monthly protection and dosage flexibility for growing kittens.
Practical Considerations
- Frequency of Dosing: Choose Credelio if you prefer monthly dosing and more control over timing; choose Bravecto for less frequent administration.
- Target Parasites: Both treat fleas effectively, but Bravecto may cover a broader range of tick species.
- Safety and Tolerance: Both drugs belong to the same class (isoxazolines), so side effect profiles are similar.
- Veterinary Guidance: Always consult your vet to select the appropriate product, especially if your pet has pre-existing medical conditions.
Conclusion
Both Bravecto and Credelio are trusted flea and tick preventatives within the isoxazoline family, offering different benefits based on your schedule and your cat’s health profile. While Credelio is ideal for pet owners wanting monthly, flexible control and proven efficacy against fleas and black-legged ticks, Bravecto provides a longer protection window with less frequent dosing.
Proper administration — especially giving Credelio with food — ensures optimal absorption and maximum protection. Monitor your cat for any side effects and consult your veterinarian to determine which product fits your pet’s needs best.





