Can Cytopoint Help with Paw Licking in Dogs?
One of the most common signs of allergic skin disease in dogs is excessive paw licking. This behavior often stems from chronic itchiness caused by environmental, food, or flea-related allergies. Fortunately, modern veterinary medicine offers solutions to manage this discomfort. One such option is
Cytopoint, a targeted therapy designed to reduce itching in dogs.
What Is Cytopoint?
Cytopoint is a prescription-only injectable medication for dogs suffering from atopic dermatitis and other pruritic (itch-related) skin conditions. Its active ingredient,
lokivetmab, is a monoclonal antibody that specifically targets and neutralizes
interleukin-31 (IL-31). IL-31 is a cytokine involved in sending itch signals to the brain, making it a primary culprit behind persistent skin irritation.
How Cytopoint Reduces Paw Licking
Many dogs lick their paws excessively due to itchiness triggered by allergic reactions. By blocking IL-31, Cytopoint interrupts the itch-scratch cycle, leading to reduced discomfort. This mechanism helps in:
- Minimizing itch sensations localized in the paws and other areas
- Preventing self-inflicted injuries like sores and inflammations from repeated licking
- Allowing skin to heal naturally without ongoing trauma
How It’s Administered
Cytopoint is given through a subcutaneous injection, typically administered by a veterinarian every 4–8 weeks, depending on the dog’s response. This treatment can start working within 1–3 days of injection and may offer relief for up to 8 weeks.
When Is Cytopoint Recommended?
Veterinarians often recommend Cytopoint for dogs who:
- Show signs of chronic itching and paw licking
- Have been diagnosed with atopic dermatitis or allergic skin diseases
- Cannot tolerate or take oral anti-itch medications
- Need a steroid-free treatment option for safer long-term use
How Effective Is Cytopoint?
Clinical studies suggest that Cytopoint is effective in about 60–75% of dogs. Some dogs experience dramatic improvements, such as:
- Significantly reduced licking and scratching
- Healthier skin and coat following reduced irritation
- Improved overall comfort and quality of life
However, responses vary among individuals. Some dogs may have only partial or temporary relief, and a veterinarian may recommend combining Cytopoint with other therapies.
Safety Profile
Cytopoint is well-tolerated in dogs of all ages, including puppies and seniors. It is particularly valued for having
fewer systemic side effects because it doesn’t broadly suppress the immune system. Reported mild side effects may include:
- Lethargy
- Pain or swelling at the injection site
- Rare allergic reactions such as hives or facial swelling
Cytopoint is safe to use alongside other medications and treatments, including vaccines, antibiotics, and flea preventatives.
Limitations and Considerations
While Cytopoint provides symptomatic relief, it does
not cure the underlying allergic condition. For long-term success, a multifaceted approach may be needed, such as:
- Allergy testing and avoidance strategies
- Use of special shampoos and topical treatments
- Flea control measures
- Dietary modifications or limited-ingredient diets
- Immunotherapy (allergy shots)
Additionally, a small percentage of dogs may develop antibodies against Cytopoint over time, reducing its effectiveness.
Access and Storage
Only licensed veterinarians can administer Cytopoint. It's not available for at-home use and must be stored in a medical-grade refrigerator (2°C–8°C / 36°F–47°F).
Cytopoint vs Other Treatments
Compared to options like Apoquel (oral medication) or steroids, Cytopoint offers:
- Targeted relief without immune suppression
- No pills to administer, ideal for fussy dogs
- Long-acting effect, with relief lasting up to 8 weeks
Conclusion
If your dog excessively licks their paws, especially due to allergy-related itching, Cytopoint may be a highly effective and safe option. It breaks the itch-lick cycle by stopping the itch signal at its source, offering rapid and sustained relief. Consult your veterinarian to determine if Cytopoint is the right choice for your canine companion. Together, you can design a treatment plan that ensures your dog’s comfort and skin health.
