Early Signs of Feline Leukemia in Cats: What to Watch For
Feline leukemia virus (FeLV) is a serious and contagious virus affecting cats, particularly those that come into contact with infected felines. Known to weaken the immune system and increase the risk of various secondary infections and cancers, feline leukemia is a concern for cat owners worldwide. Early detection is crucial to managing the quality of life and longevity of affected pets. In this article, we’ll explore the most common early signs of feline leukemia, what causes the condition, and how to care for a cat with FeLV.
What Is Feline Leukemia?
Feline leukemia virus is a retrovirus that integrates into the host’s DNA. It is primarily spread through close contact, such as grooming, sharing water bowls, bite wounds, and from mother cats to kittens. FeLV can lead to immunosuppression, anemia, and cancers such as lymphoma.
First Signs of Feline Leukemia
The early symptoms of feline leukemia are often subtle and can be mistakenly attributed to other minor ailments. However, being aware of these signs can prompt timely veterinary care and testing:
- Lethargy: A noticeable decrease in activity and enthusiasm is one of the most common early signs. Cats with FeLV may sleep more and show a lack of interest in play or interaction.
- Fever: A low-grade fever may be persistent or intermittent, often going unnoticed without a thermometer.
- Loss of Appetite: Cats may begin to eat less or become picky about their food, leading to gradual weight loss.
- Weight Loss: Dramatic or unexplained weight loss is a red flag and could indicate an internal illness such as FeLV.
- Swollen Lymph Nodes: Enlarged lymph nodes are a common immune response to viral infections, including FeLV. A vet can palpate and examine these areas.
- Gingivitis or Stomatitis: Red, inflamed gums and mouth ulcers are frequent findings in FeLV-positive cats due to immune system suppression.
- Recurring Infections: Because the virus compromises immunity, cats may experience persistent or recurrent infections like upper respiratory tract infections, skin infections, or gastrointestinal issues.
- Pale Gums: Anemia caused by FeLV may present as whiteness or pallor in the cat’s gums and mucous membranes.
- Diarrhea: Gastrointestinal upset and chronic diarrhea can also be signs of underlying FeLV, especially when accompanied by weight loss.
- Behavioral Changes: Increased hiding, irritability, or reduced social interaction may indicate discomfort or sickness.
Important Considerations
Feline leukemia is not curable, but with supportive care, infected cats can live comfortably for years. Testing is typically done using in-clinic ELISA (enzyme-linked immunosorbent assay) tests, followed by confirmatory IFA (immunofluorescence assay) if needed.
How Is FeLV Diagnosed?
- Physical Examination: A thorough checkup can reveal clinical signs like lymphadenopathy or pale gums.
- Blood Tests: The ELISA test detects viral antigens in the blood. Positive results usually warrant further analysis using IFA testing or PCR.
- Follow-up Testing: Repeat testing after a few months helps confirm persistent infection, particularly in young cats who might initially test positive but clear the virus.
Preventing Feline Leukemia
Preventing FeLV is more effective than treating it. Consider these preventative measures:
- Vaccination: While not 100% effective, FeLV vaccines significantly reduce the risk of infection.
- Indoor Lifestyle: Keeping cats indoors prevents exposure to feral or infected outdoor cats.
- Testing New Cats: Always test new kittens or cats before introducing them to a multi-cat household.
- Hygiene and Cleanliness: Regularly clean shared bowls, litter boxes, and bedding to minimize risk.
Living with a FeLV-Positive Cat
Cats diagnosed with feline leukemia can still enjoy high-quality lives under the right care:
- Maintain regular veterinary check-ups to monitor their health status.
- Feed them a high-quality, balanced diet.
- Avoid raw food diets, which may contain harmful pathogens their weakened immune systems cannot combat.
- Minimize stress and provide a stable, enriching environment.
- Keep them indoors to reduce exposure to pathogens and to prevent spreading the virus to other cats.
Conclusion
Recognizing the first signs of feline leukemia can significantly impact the supportive care and management of the disease. Early symptoms such as fatigue, reduced appetite, weight loss, and recurring infections should not be ignored. If you suspect something is wrong with your cat, consult a veterinarian immediately for appropriate FeLV testing.





