Safe Use of Dramamine for Dogs: What Pet Owners Need to Know
Dramamine, known generically as dimenhydrinate, is a commonly used medication to treat and prevent motion sickness in both humans and dogs. While not originally developed for animals, many veterinarians recommend its off-label use in dogs to manage symptoms like nausea, vomiting, drooling, restlessness, and anxiety during various types of travel.
What Is Dramamine?
Dramamine is an antihistamine that works by reducing the stimulation of the inner ear and suppressing signals in the brain that cause nausea and vomiting. In veterinary medicine, it is often used to help dogs cope with motion sickness or vestibular disease, particularly common in older dogs.
Formulations and Safe Versions
Dramamine is available in several human formulations:
- Regular tablets
- Chewable tablets
- Oral liquid
The safest version for dogs is the one that contains dimenhydrinate as the only active ingredient. Avoid products with additional agents such as ginger or the “non-drowsy” versions that often contain other active components like meclizine. These can be unsafe or not well-tolerated in dogs.
Correct Dosage Guidelines
It's essential to use proper dosing when giving Dramamine to your dog:
- Typical dosage: 2 to 4 mg per pound of body weight
- Administered every 8 hours or as directed by a veterinarian
- Time of administration: Give 30 to 60 minutes before travel to ensure effectiveness
Always check dosage with your veterinarian, especially for small dogs under 6 pounds or those with health conditions.
Benefits of Use
- Reduces travel-related nausea and vomiting
- Minimizes anxiety-related behaviors (whining, drooling, panting)
- Can be helpful in treating vestibular disease
- May improve your pet's comfort during long trips
Potential Side Effects
Although generally well-tolerated, Dramamine can cause side effects in some dogs:
- Drowsiness or sedation - often beneficial for anxious travelers
- Dry mouth and increased thirst
- Urinary retention or difficulty urinating
- Loss of appetite or vomiting
- Rare but possible: hyperactivity, allergic reactions, seizures, or coma
Warnings and Contraindications
Use Dramamine cautiously or avoid it if your dog has:
- Glaucoma
- Seizure disorders
- Thyroid issues
- Heart or respiratory conditions
- Urinary or intestinal blockages
It should not be administered to neonatal dogs or within two weeks of allergy testing.
Drug Interactions
Dramamine may interact with other medications. Inform your veterinarian if your dog is taking:
- Other antihistamines
- Sedatives or muscle relaxants
- Opioids
- Antidepressants
- Benzodiazepines (e.g., diazepam)
- Anti-seizure or anticholinergic drugs
What to Do in Special Cases
Missed dose: Administer as soon as you remember, but never double up.
Storage: Keep product at room temperature; protect liquid forms from freezing.
Overdose: Contact your vet or nearest emergency clinic immediately.
Alternatives to Dramamine
If Dramamine isn’t effective or causes side effects, consider these alternatives:
- Other antihistamines: Benadryl (diphenhydramine), cetirizine, chlorphenamine
- Prescription meds: Cerenia (maropitant citrate), gabapentin, trazodone
- Behavioral therapies and calming wraps
- Gradual exposure to car rides
- Natural supplements like ginger
Conclusion
Dramamine containing dimenhydrinate can be safe and effective for dogs when used under veterinary supervision. It should be part of a comprehensive approach to managing motion sickness that includes proper planning, environmental adjustments, and monitoring for side effects. Always consult your veterinarian before starting any new medication to ensure your dog’s safety and optimal care.





