Understanding Epididymitis in Dogs: Symptoms, Causes, and Diagnosis
Epididymitis is an inflammation of the epididymis — a coiled tube located at the back of the testicles, crucial for the storage and transport of sperm. Although relatively uncommon, this condition can cause significant discomfort and impact fertility in intact male dogs, particularly as they age.
Recognizing the Clinical Signs of Epididymitis
Owners may not immediately recognize the subtle signs of epididymitis in their dogs. However, there are several key indicators:
- Pain and swelling localized to the testicle or epididymis
- Scrotal edema and excoriation (skin irritation or damage)
- Enlargement or abnormal morphology of the epididymis
- Palpable nodules or masses in the scrotal area
- Decreased libido and poor semen quality
- Infertility or subfertility
- Behavioral changes such as reluctance to be touched or increased irritability
- Scrotal ulceration due to self-trauma in chronic cases
Common Causes of Epididymitis in Dogs
Epididymitis can develop from several underlying factors. The most frequent causes include:
- Bacterial infections: Brucella canis and Escherichia coli are common offenders
- Fungal or viral infections
- Immune-mediated inflammation
- Trauma, hormonal imbalances, or surgical interventions (e.g., vasectomy)
- Congenital ductal abnormalities
Epididymitis often occurs alongside orchitis (testicular inflammation), forming a condition known as epididymo-orchitis.
Diagnosing Epididymitis in Dogs
Prompt veterinary evaluation is critical. Diagnosis may involve:
- Physical examination and palpation
- Ultrasound imaging (including color Doppler) to assess structure and blood flow
- Fine needle aspiration or biopsy to analyze tissue or masses
- Bacterial or fungal cultures to identify infectious agents
- Semen analysis to evaluate fertility
- Blood tests to assess systemic infection or inflammation
A key diagnostic step is testing for Brucella canis, a zoonotic pathogen. Infected dogs require isolation and often castration, as no effective medical treatment currently exists.
Associated Conditions: Granulomas and Cysts
Chronic or severe epididymitis may lead to:
- Sperm granulomas: Inflammatory reactions caused by sperm leakage into nearby tissues from obstructed or ruptured ducts
- Spermatoceles (sperm cysts): Fluid-filled sacs typically forming due to ductal blockage
These conditions may present as painless nodules or swelling and often result in infertility when bilateral. Surgical removal is often the only effective treatment.
Differential Diagnoses
Several other conditions can mimic epididymitis, necessitating careful diagnosis:
- Testicular tumors (seminomas, Sertoli cell tumors, Leydig cell tumors)
- Congenital anomalies (segmental aplasia, hypoplasia)
- Adenomyosis and epithelial hyperplasia
- Trauma or previous surgical complications
Treatment and Prognosis
Early intervention maximizes outcomes. Depending on the cause and severity, treatment may include:
- Antibiotics or antifungal agents if an infection is present
- Anti-inflammatory medications to reduce swelling and pain
- Surgical castration in severe, chronic, or Brucella-positive cases
Dogs with sperm granulomas or cysts rarely improve without surgery, especially when bilateral.
Prevention and Long-Term Care
- Neutering dogs not intended for breeding can prevent many testicular and epididymal conditions
- Regular veterinary exams for intact males can detect early signs of reproductive disease
- Prompt evaluation of any scrotal swelling, discomfort, or behavioral shift helps ensure timely treatment
Understanding the causes and symptoms of epididymitis is essential for proactive pet care, particularly for breeding males or aging intact dogs. With vigilance and veterinary support, owners can manage and often prevent serious reproductive complications in their canine companions.





