Which Dogs Should Avoid NexGard PLUS? A Comprehensive Guide for Pet Owners
NexGard PLUS is a powerful, convenient monthly chewable that protects dogs from a range of parasites including fleas, ticks, heartworms, roundworms, and hookworms. While it's an effective treatment for many dogs, there are specific cases where NexGard PLUS may not be suitable. Understanding the precautions and safety considerations can help pet owners make informed decisions in consultation with their veterinarian.Key Ingredients and Their Roles
NexGard PLUS combines three active ingredients:- Afoxolaner: Kills adult fleas and ticks.
 - Moxidectin: Prevents heartworm disease by eliminating larvae.
 - Pyrantel: Treats and controls hookworm and roundworm infections.
 
Dogs That Should Avoid NexGard PLUS
1. Dogs with a history of seizures or neurologic disordersAfoxolaner is part of the isoxazoline class, which has been associated with neurologic side effects such as tremors, ataxia (loss of coordination), and seizures. While these reactions are relatively rare, dogs with pre-existing neurologic issues should only use the product with veterinary supervision. 2. Pregnant, breeding, or lactating dogs
The safety of NexGard PLUS in pregnant, breeding, or nursing dogs has not been evaluated. Consequently, it's best to avoid use in these populations unless otherwise advised by a veterinarian. 3. Dogs under 8 weeks old or less than 4 pounds
NexGard PLUS is only approved for puppies and adult dogs that are at least 8 weeks old and weigh 4 pounds or more. Giving the medication to dogs outside this range may result in inappropriate dosing and potential adverse effects. 4. Dogs with an existing adult heartworm infection
While NexGard PLUS prevents heartworm disease, it is not effective against adult Dirofilaria immitis (mature heartworms). Dogs must be tested for current heartworm infections before starting the medication.
Common Side Effects and Reactions
In clinical trials, the most commonly reported adverse reactions included:- Vomiting
 - Diarrhea
 - Lethargy
 - Itching
 
Important Administration Notes
- NexGard PLUS should be given once a month on the same day each month.
 - It can be given with or without food.
 - If a dog vomits within two hours of administration, a replacement dose may be necessary.
 - Never store a partially used chew; single-use only.
 
Veterinary Supervision Is Key
All dogs should have a veterinary exam and a heartworm test before beginning NexGard PLUS. Even if a dog seems healthy, a background of medical issues may present unseen risks when using preventive medications. Veterinarians may recommend alternative treatments or conduct additional tests based on your dog’s medical history.Dogs That Can Safely Use NexGard PLUS
NexGard PLUS is safe for most dogs that:- Are 8 weeks of age or older
 - Weigh at least 4 pounds
 - Have no history of neurologic symptoms
 - Are not pregnant or nursing
 
Concurrent Medications
In clinical studies, NexGard PLUS was safely used alongside common medications such as:- Vaccines
 - Antibiotics
 - Anti-inflammatories
 - Anaesthetics
 - Steroids
 - Antiparasitics
 





