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What is the controversy with the Seresto flea collar?

The controversy centers on reports of pet deaths and adverse reactions potentially linked to Seresto flea collars, prompting an EPA review and regulatory actions.

Understanding the Controversy Surrounding Seresto Flea Collars

The Seresto flea and tick collar, produced by Elanco Animal Health, has become a widely used method for preventing flea and tick infestations in dogs and cats. Despite over 70 million units sold globally and widespread use across more than 80 countries, the product has come under scrutiny due to concerns about safety and potential adverse effects.

Composition and Function of Seresto Collars

Each Seresto collar contains two active ingredients:

  • Imidacloprid — a neonicotinoid insecticide effective against fleas.
  • Flumethrin — a pyrethroid used to repel and kill ticks.

The collar technology uses a polymer matrix to release these ingredients slowly over eight months, providing long-term, water-resistant protection for pets. The substances are distributed across the pet’s skin and coat, not absorbed into the bloodstream.

Federal Safety Reviews and Reported Incidents

The U.S. Environmental Protection Agency (EPA) began a thorough review of Seresto collars in 2021 after receiving approximately 1,400 pet death reports between 2016 and 2020. However, many reports lacked comprehensive data, making it difficult to determine a direct link between the collar and the fatalities.

Key findings include:

  • Most confirmed fatalities were due to mechanical accidents such as collar-related strangulation or trauma.
  • Other reports could not definitively tie deaths to the collar due to pre-existing conditions.
  • Non-lethal events included localized skin irritation, hair loss, and in rarer cases, neurological symptoms such as convulsions or ataxia.

Many side effects resolved after the collar was removed. Reintroducing the collar sometimes reinstated the symptoms.

EPA Actions and Manufacturer Response

In response to these incidents, the EPA mandated several changes:

  • Stronger label warnings highlighting potential risks and symptoms to monitor.
  • Improved data collection on incident reports, including background medical histories of pets.
  • Annual safety and sales reporting required from Elanco.
  • Evaluation of the collar’s release mechanism to reduce accidental strangulation.
  • The Seresto registration remains valid for five years, pending annual safety reviews.

Elanco's internal monitoring suggests the death rate from the collar is less than 0.2% and that most reactions are mild and reversible. They maintain that active ingredients have not been linked to any deaths based on toxicological evidence.

The Issue of Counterfeit Collars

A significant concern contributing to adverse outcomes has been the circulation of counterfeit Seresto collars. These often lack proper chemical formulations and safety mechanisms, leading to a higher rate of negative incidents.

  • Counterfeits are commonly sold through unauthorized online sellers.
  • Veterinarians recommend obtaining collars directly from clinics or trusted retailers.

Guidelines for Safe Use

To reduce risk, pet owners should:

  • Monitor pets closely after applying the collar, particularly in the first few days.
  • Check for symptoms like redness, irritation, lethargy, GI upset, or behavioral changes.
  • Remove the collar immediately if adverse reactions are seen and consult a vet.
  • Avoid frequent bathing (preferably not more than once monthly) as it can affect collar efficacy.
  • Consult professionals before using the collar on pregnant or lactating pets.

Veterinary Recommendations and Efficacy

Veterinarians generally support continued use of Seresto in preventing flea and tick-related diseases, emphasizing that:

  • Adverse events are rare compared to the volume sold.
  • Correct usage drastically reduces negative outcomes.
  • Risks from infestations (e.g., Lyme disease, anemia) typically outweigh collar risks.

Conclusion

While the controversy over Seresto flea collars is not without merit, especially given the reported fatalities, regulatory reviews and scientific analysis largely support their safety when used properly. Pet owners are advised to remain vigilant, purchase only from reputable sources, and follow all usage instructions diligently. For any concerns or alternatives, veterinarians should serve as the first point of contact.

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