Which Dogs Are Most at Risk for Lyme Disease?
Lyme disease is a widespread tick-borne illness in dogs, caused primarily by the spirochete bacterium Borrelia burgdorferi. Transmission occurs via the bite of infected blacklegged ticks, including Ixodes scapularis (deer ticks) and Ixodes pacificus on the Pacific Coast. Dogs become infected when bitten by a tick that remains attached for at least 24–48 hours.
High-Risk Regions for Lyme Disease
- Northeastern United States
- Upper Midwestern United States
- Parts of the mid-Atlantic
- Certain Pacific Coast areas
- Eastern Canada
Dogs living in or frequently traveling to these areas are at a significantly higher risk of exposure.
Environmental Risk Factors
The chances of infection increase for dogs that:
- Live near or visit wooded, bushy, or grassy areas
- Have outdoor lifestyles, especially without tick protection
- Are not regularly inspected for ticks
Dogs exposed to ticks often do not show immediate symptoms. When symptoms appear, they may include:
- Fever and lethargy
- Swollen lymph nodes
- Joint pain or shifting lameness
- Stiffness and reduced appetite
Breeds and Health Conditions Affecting Risk
No breed is inherently immune to Lyme disease, but certain dogs may face complications. Dogs genetically predisposed to kidney disease, especially retrievers, should be monitored carefully. Additionally, small breeds such as:
- Dachshunds
- Chihuahuas
- Pugs
- Boston Terriers
- Miniature Pinschers
may be more prone to vaccine reactions and should be evaluated by a veterinarian before immunization.
Diagnosis and Monitoring
Diagnosis often involves assessing clinical signs and conducting serologic tests such as the SNAP 4Dx. Even asymptomatic dogs in high-risk areas may test positive for exposure.
Essential Prevention Measures
Because no prevention is 100% effective, a multi-pronged approach is critical:
- Tick Preventatives: Routinely apply prescription oral or topical medications.
- Daily Tick Checks: Carefully inspect dogs' skin and coats, focusing on ears, neck, and undercarriage.
- Lyme Vaccination: Recommended for at-risk dogs, beginning at 8 weeks with boosters as advised by a vet.
Types of Lyme Vaccines
Vaccines vary in composition and strategy:
- Subunit vaccines: Use outer surface protein A (OspA), sometimes combined with OspC or chimeric versions for broader protection.
- Bacterin vaccines: Contain killed whole-cell Borrelia lysates.
OspA-based vaccines induce antibodies capable of killing Borrelia inside the tick during feeding, halting transmission.
Considerations Before Vaccination
Vaccination decisions should consider:
- Geographic location and travel history
- Level of outdoor exposure
- Medical history and breed predispositions
Dogs with a history of Lyme nephritis or existing protein-losing kidney disease should not be vaccinated.
Summary for Pet Owners
- Ticks are active even in cold weather—use preventatives all year.
- Vaccinate dogs at risk, but only after consulting a veterinarian.
- Even vaccinated dogs need tick control and regular checks.
- Monitor for side effects following vaccination, especially in small breeds.
In conclusion, dogs most at risk for Lyme disease are those routinely exposed to ticks in endemic areas and lacking proper tick prevention. A discussion with a veterinarian can tailor the right protection strategy for individual dogs.





