Nexgard vs. Bravecto: Which Flea and Tick Preventative is Safer?
Choosing the right flea and tick prevention product is vital for your dog's health. Among the most popular options are Nexgard and Bravecto, both of which are veterinary-approved oral medications that protect dogs from parasites. However, when it comes to safety, one is not universally better than the other. It's essential to understand how each works, their active ingredients, effectiveness, potential side effects, and what factors should influence your decision.
Understanding Nexgard and Bravecto
- Nexgard: A monthly chewable that contains afoxolaner, which kills fleas and ticks by overexciting their nervous systems.
- Bravecto: A chewable tablet given once every 12 weeks, containing fluralaner, which also targets the nervous system of parasites, killing them upon contact.
Safety Considerations
Both medications have been extensively tested and are FDA-approved for use in dogs, meaning they're considered safe when used according to veterinary guidelines. However, no medication is entirely risk-free, and tolerability varies between individual dogs.
Common Side Effects
- Nexgard: Vomiting, lethargy, dry/flaky skin, and diarrhea.
- Bravecto: Vomiting, decreased appetite, diarrhea, and lethargy.
Both are generally well-tolerated, but dogs with certain health conditions may be more prone to side effects.
Factors Influencing Safety
- Breed and Genetics: Dogs with the MDR1 gene mutation (e.g., Collies, Australian Shepherds, Shelties) may be more sensitive to some medications.
- Age and Weight: Safe use depends on a dog meeting the minimum age and weight guidelines outlined on the product label.
- Health History: Dogs with a history of seizures or neurological issues should be evaluated carefully before using oral preventatives like Nexgard or Bravecto.
Administration Method
These medications offer excellent convenience via oral chewables, eliminating risks associated with topical treatments such as exposure to other pets or children. However, they rely on the dog fully ingesting the dose.
Parasite Coverage
While both products focus on flea and tick elimination, they do not prevent worm infestations or repel ticks before they attach. Some pet owners prefer combination products such as Simparica Trio or Credelio Quattro for broader protection.
Veterinary Consultation is Key
Your veterinarian will assess multiple factors before prescribing a product:
- Geographic risks for specific tick-borne diseases
- Your dog’s activity level and environmental exposure
- Existing medical conditions and medications
Veterinarians may recommend one over the other based on lifestyle, breed sensitivity, and previous reactions.
Which Is Safer?
There is no definitive answer to whether Nexgard or Bravecto is safer; both have robust safety profiles when administered correctly. However:
- Nexgard's monthly dosing may allow for quicker detection of reactions.
- Bravecto requires less frequent dosing, which can be better for dogs who don't tolerate frequent medication.
Ultimately, the right choice depends on your dog’s unique needs and veterinary advice.
Best Practices for Flea and Tick Prevention
- Always follow veterinary recommendations for product selection and dosage.
- Monitor your dog after administering any new treatment for side effects.
- Keep treatments consistent year-round, as flea and tick threats persist regardless of season.
In conclusion, both Nexgard and Bravecto are effective and considered safe. Choosing the most appropriate one requires a customized approach guided by your veterinarian. Your dog’s safety and well-being should always be the top priority when selecting a flea and tick preventative.





