Background
  1. Home
  2. News
  3. FAQ
  4. What is the most common cause of death in indoor cats?

What is the most common cause of death in indoor cats?

The most common cause of death in indoor cats is cancer, particularly lymphoma, followed by kidney disease and heart disease.

Leading Causes of Death in Indoor Cats

Indoor cats generally live longer, healthier lives than their outdoor counterparts, but they are not immune to disease. Understanding the most common causes of death in indoor cats can empower pet owners to take proactive measures. This article explores the primary illnesses contributing to feline mortality, how to recognize early signs, and what you can do to improve your cat's well-being.

1. Cancer – The Most Common Cause

Lymphoma, a type of blood cancer, is the most prevalent cancer and the leading cause of death in indoor cats. It often affects the gastrointestinal system, lymph nodes, and other organs. Key signs of feline cancer include:
  • Unexplained weight loss
  • Vomiting or diarrhea
  • Lethargy
  • Loss of appetite
  • Visible or palpable masses on the body
Early detection through regular veterinary exams, bloodwork, and imaging increases the chances of effective treatment.

2. Chronic Kidney Disease (CKD)

Cats are particularly prone to chronic kidney disease, especially as they age. The kidneys gradually lose function, leading to toxin buildup in the bloodstream. Common symptoms of CKD:
  • Increased thirst and urination
  • Weight loss
  • Poor coat condition
  • Vomiting and bad breath
  • Lack of energy
While CKD is progressive and incurable, early diagnosis and a prescription renal diet can extend a cat's life by months or even years.

3. Heart Disease

Hypertrophic cardiomyopathy (HCM) is the most common form of heart disease in cats. It causes the heart muscle to thicken, reducing cardiac function and potentially leading to sudden death. Warning signs of heart disease include:
  • Rapid or labored breathing
  • Fainting or collapsing
  • Loss of appetite
  • Restlessness
Cats with undiagnosed HCM often show no symptoms until it’s too late, making annual vet checkups and echocardiograms critical, particularly for breeds predisposed to HCM.

4. Feline Infectious Peritonitis (FIP)

Although relatively rare in indoor-only cats, FIP remains a fatal disease caused by a mutation in the feline coronavirus. A new treatment, GS-441524, has shown promise but is not yet widely available.

5. Diabetes Mellitus

Feline diabetes, especially Type 2, is increasingly common due to indoor cats' sedentary lifestyles and high-carbohydrate diets. If unmanaged, it can lead to a dangerous condition called ketoacidosis.

6. Accidents and Environmental Hazards

While rare, indoor cats can die from:
  • Fall injuries from high windows (High-Rise Syndrome)
  • Choking on small objects
  • Toxic exposure (e.g., lilies, human medications)

Preventive Measures to Extend Your Cat’s Life

  • Routine vet visits for physicals, bloodwork, and vaccines
  • Healthy diet with proper hydration and few carbs
  • Exercise and mental stimulation to reduce obesity risk
  • Safe environment free of toxic plants and fall hazards

Conclusion

While cancer is the leading cause of death in indoor cats, other chronic diseases like kidney and heart conditions follow close behind. Proactive care, early diagnosis, and a safe, enriched environment can greatly improve both the quality and length of your indoor cat’s life.

Share on:

indoor cat health

 causes of cat death

 feline cancer

 chronic kidney disease in cats

 hypertrophic cardiomyopathy

 cat lymphoma

 indoor cat lifespan

 most common cat illness

 signs of cancer in cats

 cat heart disease

 feline diabetes

 kidney failure in cats

 cat diseases

 fip in cats

 prevent cat illness

 cat care tips

 feline health

 cat health risks

 veterinary cat checkups

 cat diet and disease

 symptoms of cat illness

 older cat health

 indoor cat safety

 cat mortality

 common feline problems

Recommended

Various dogs and cats available for adoption in a shelter

Multnomah County Animal Services Slashes Adoption Fees to Combat Shelter Overcrowding

Read the article

Fluffy gray Maine Coon cat reaching towards a bright red poppy flower in a garden

50+ Celtic Cat Names: Magical Choices from Irish and Scottish Heritage

Read the article

Majestic Maine Coon cat lounging gracefully on a light-colored couch near a sunlit window

How to Get Poop Smell Out of Couch: A Complete Cleaning Guide

Read the article

Today is the perfect time to get your

Pet Health Report

Upload a photo of your pet to receive instant health and care insights. Personalized, smart, and completely free.

report_card