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The 3:2:1 rule in cats refers to a vaccination protocol where kittens receive initial vaccine doses every 3–4 weeks until 16–20 weeks old, followed by a booster at 1 year, and then boosters every 1 to 3 years depending on risk and vaccine type.
If a cat doesn't receive a distemper shot, it is at high risk of contracting feline panleukopenia, a highly contagious and often fatal viral disease.
The 3:2:1 rule in cats refers to the vaccination protocol for feline panleukopenia, where kittens receive 3 initial doses, 2 to 4 weeks apart, starting at 6–8 weeks of age, followed by 1 booster after one year.
If a cat doesn't get a distemper shot, it is at high risk of contracting feline panleukopenia—a severe, often fatal, and highly contagious viral disease.
The 3:2:1 rule in cats refers to the recommended feline distemper vaccination schedule: three initial vaccines, two to four weeks apart, and one booster after a year.
If a cat doesn't receive a distemper vaccine, it risks contracting feline panleukopenia, a highly contagious and potentially fatal virus, especially in kittens.
Cats should receive feline distemper (FVRCP) shots starting at 6–8 weeks with boosters every 3–4 weeks until 16–20 weeks old, then a booster at 1 year, followed by every 1–3 years.
Signs of feline distemper include fever, vomiting, diarrhea, lethargy, dehydration, and in kittens, neurological symptoms like tremors and incoordination.
A distemper shot protects cats from feline panleukopenia, a highly contagious and potentially fatal viral disease affecting the immune and gastrointestinal systems.
Yes, indoor cats still need distemper shots because the virus is highly contagious and can be carried into the home via shoes, clothing, or other pets.

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